UroToday3d
Transformative or Transitional? Deciphering the Role of NIAGARA in Shaping Future Practice - Beyond the Abstract
The phase 3 NIAGARA trial has introduced promising advancements in the treatment landscape for muscle-invasive bladder cancer (MIBC). By integrating perioperative durvalumab with neoadjuvant cisplatin ...
UroToday3d
AI Allows Pre-Screening of FGFR3 Mutational Status Using Routine Histology Slides of Muscle-Invasive Bladder Cancer - Beyond the Abstract
Urothelial carcinoma (UC) of the bladder ranks among the most prevalent malignancies worldwide, with a particularly high incidence in males. A majority of patients initially present with non-muscle ...
UroToday3d
Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer.
Enzalutamide is a potent second-generation antiandrogen commonly used to treat hormone-sensitive and castration-resistant prostate cancer (CRPC) patients. While initially effective, the disease almost ...
UroToday3d
Impact of late effects after treatment for bladder cancer with radical cystectomy on Quality of life: a case-control study.
The gold standard when treating muscle-invasive bladder cancer (MIBC) is radical cystectomy (RC), a procedure that holds the potential to affect the function of several pelvic organs, causing an ...
UroToday3d
Diagnostic performance of artificial intelligence in detection of renal cell carcinoma: a systematic review and meta-analysis.
The detection of renal cell carcinoma (RCC) tumors in the earlier stages is of great importance for more effective treatment. Encouraged by the key role of imaging in the management of RCC, we ...
UroToday3d
Development of point-of-care tests for urinary bladder cancer - an historic review and view to future prospectives.
Urine is an attractive biospecimen for noninvasive tests to facilitate bladder tumor diagnostics. Three different point-of-care (POC) tests based on lateral flow immunoassays (LFAs) are currently ...
UroToday3d
New Mediastinal and Hilar Lymphadenopathy After Adjuvant Pembrolizumab in a Patient With Stage III Clear Cell Renal Cell Carcinoma.
The advent of immune checkpoint inhibitors (ICIs) has transformed the management of advanced and high-risk renal cell carcinoma (RCC). In the adjuvant setting, ICIs, such as pembrolizumab, aim to ...
UroToday3d
MAPK1IP1L::TFE3-rearranged renal cell carcinoma: a novel fusion adding to the differential diagnosis of oncocytic renal neoplasms.
Beyond the more common TFE3 fusion partners PRCC, ASPSCR1, and SFPQ, additional less common fusion partners of TFE3-rearranged renal cell carcinoma (RCC) have been described. Herein, we present an ...
UroToday3d
Refining partial gland ablation for localised prostate cancer: the FALCON project.
To provide a contemporary statement on focal therapy (FT) for localised prostate cancer (PCa) from an international and diverse group of physicians treating localised PCa, with the aim of overcoming ...
UroToday3d
Ultra-fast biparametric MRI in prostate cancer assessment: Diagnostic performance and image quality compared to conventional multiparametric MRI.
To compare the diagnostic performance and image quality of a deep-learning-assisted ultra-fast biparametric MRI (bpMRI) with the conventional multiparametric MRI (mpMRI) for the diagnosis of ...
UroToday4d
Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy.
Platinum-based neoadjuvant chemotherapy prior to radical cystectomy is the preferred treatment for muscle-invasive bladder cancer despite modest survival benefit and significant associated toxicities.
UroToday6d
Long-term effects of superselective renal artery embolization on renal function after percutaneous nephrolithotomy.
To investigate the long-term impact of superselective renal artery embolization (SRAE) on renal function in cases of severe post-percutaneous nephrolithotomy (PCNL) haemorrhage, and to identify the ...