See related article at In a related analysis, Abdel-Rahman and colleagues[1][2] discuss how the marked improvement in quantity and quality of life experienced by some people with cancer who receive ...

An 81-year-old man presented to the emergency department after 2 episodes of uncontrollable shaking, each lasting several minutes, accompanied by a sensation of extreme cold. He and his partner stated ...

In research published in this issue of CMAJ, Mah and colleagues summarize clinicians’ experiences of providing care for patients whose presenting illness is not acute and for whom admission to ...

A 32-year-old woman presented to our emergency department 2 days after the onset of bilateral hand swelling. Two weeks earlier, her 8-year-old son had had an erythematous rash on both cheeks. A week ...

Velina Tzankova, Werner J. Becker and Tommy L.H. Chan Migraine is a leading cause of disability across all age groups. Routine imaging is not recommended in patients with migraine who have no red ...

Although Canada’s absolute physician-to-population ratio has increased and is at an historic high, reports of physician shortages and inadequate patient access to physicians abound. To reconcile these ...

Chimeric antigen receptor T-cell therapy (CAR-T) is a targeted, gene-edited cell therapy for cancer that is approved in Canada for relapsed or refractory high-grade B-cell lymphoma and B-cell acute ...

Transgender individuals experience high rates of violence, discrimination and homelessness. Psychiatric disorders should be managed before or concurrent with medical transition for gender dysphoria.

See related guideline at Key points Arterial hypertension is the leading and most important risk factor for all-cause morbidity and mortality worldwide.[1][2] This is because high blood pressure ...

In January 2018, Dr. Tyndall advocated for prescribing hydromorphone as a response to the presence of illicitly manufactured fentanyl in the street opioid supply.1 Two years later, the opioid crisis ...

Delirium occurs in 30%–50% of adults aged 65 years or older admitted to hospital, and may be hypoactive (lethargy, reduced psychomotor functioning), hyperactive (agitation, hallucinations) or mixed.1 ...

Subsequent to our recent CMAJ article on oral immunotherapy,1 we received a question regarding the long-term monitoring of children who undergo this therapy for food allergies and their potential risk ...