Reuters

Novo Nordisk shuts cell therapy unit amid restructuring

Oct 10 (Reuters) - Novo Nordisk (NOVOb.CO), opens new tab has decided to discontinue its cell therapy research and development efforts, a spokesperson for the Danish drugmaker told Reuters on Friday.
EMBO Press

Mitochondrial damage drives T-cell immunometabolic paralysis after major surgery

Major surgery is associated with transient suppression of T-cell immunity, increasing susceptibility to severe infections. This study identifies a previously unrecognized mechanism that drives ...
EurekAlert!

How cell cycle status affects aging cell response to senolytic drugs

Figure 6. Senescent heterogeneity model based on DNA content. Compared to G1-arrested cells, G2-arrested senescent cells express higher levels of senescence-associated markers, secrete more IL-6, and ...
C&EN

Glabridin from Glycyrrhiza glabra L. Exhibits Anti-Triple-Negative Breast Cancer Effects by Regulating Various Cell Cycle Genes

College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China Department of breast surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and ...
The Brown Daily Herald

‘A completely new world’: Yale Stem Cell Center director discusses novel gene regulation research

On Wednesday afternoon, Haifan Lin, the director of the Yale Stem Cell Center, discussed his innovative research findings in stem cell gene expression and regulation at Brown’s 2025 Mac V. Edds ...
The EMBO Journal

Nrm1 is a bistable switch connecting cell cycle progression to transcriptional control

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Entry into the cell cycle requires activation ...
SciELO

Bee venom exhibits anti-cancer effects on tongue carcinoma cells by arresting cell cycle, inducing apoptosis, and suppressing cell migration

Objective Tongue squamous cell carcinoma (TSCC) is an aggressive oral cancer with notable treatment resistance. This in vitro study investigated anti-cancer effects of honey bee venom (BV)—a mixture ...
IEEE

Connecting Different Approaches for Cell Cycle Modeling: Learning Ordinary Differential Equations from Individual-Based Models

Abstract: We investigate the feasibility of deriving surrogate ordinary differential equations (ODEs) from individual-based models (IBMs) simulated in the PhysiCell platform. As a preliminary ...
Benzinga.com

Vinay Prasad's Appointment To FDA's CBER Triggers Questions Over Future Of Cell And Gene Therapy Regulation

FDA Commissioner Marty Makary on Tuesday named Vinay Prasad the next director of the U.S. Food and Drug Administration’s (FDA) Center of Biologics Evaluation and Research (CBER). Dr. Prasad has openly ...
Frontiers

PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution

Background: Fine particulate matter (PM2.5) exposure has been associated with adverse effects on reproduction, yet the underlying cellular mechanisms remain poorly understood. Methods: Using ...
C&EN

Label-Free Exosomal SERS Detection Assisted by Machine Learning for Accurately Discriminating Cell Cycle Stages and Revealing the Molecular Mechanisms during the Mitotic Process

State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China School of Applied Chemistry and Engineering, ...