The development of cancer therapies is a long and arduous process. Because it can take several years for a cancer agent to pass clinical testing and be approved for use, terminal cancer patients ...

Background Payment of healthy volunteers in medical research is a prevalent practice but is the subject of ethical debate. Although regulations to protect healthy volunteers exist, these regulations ...

Breastfeeding advocates have criticised the phrase ‘breast is best’ as mistakenly representing breastfeeding as a departure from the norm rather than the default for infant feeding. Breastfeeding ...

Mr M Doucet, Department of Philosophy, John Watson Hall, Queen’s University, Kingston, Ontario, Canada K7L 3N6; 1wmd1{at}queensu.ca More than 40 primary studies, and three recent systematic reviews ...

Design of clinical trials for germline gene editing stretches current accepted standards for human subjects research. Among the challenges involved is a set of issues concerning intergenerational ...

Department of Hematology, Oncology and Tumor Immunology, Robert-Roessle-Clinic at the HELIOS Klinikum Berlin, Charite Medical School, Berlin, Germany Objectives: To elicit the perceptions and ...

Objectives Medical futility at the end of life is a growing challenge to medicine. The goals of the authors were to elucidate how clinicians define futility, when they perceive life-sustaining ...

Correspondence to Professor John McMillan, Bioethics Centre, University of Otago, Dunedin 9054, Otago, New Zealand; john.r.mcmillan68{at}gmail.com One set of worries concerns authorship and whether it ...

Predictive tools made possible by advances in machine learning techniques may help clinicians make more accurate decisions about who should be allocated costly therapies, such as immunotherapy, which ...

In this article, I critique the commonly accepted distinction between commercial and altruistic surrogacy arrangements. The moral legitimacy of surrogacy, I claim, does not hinge on whether it is paid ...

This paper discusses some of the ethical and legal issues that the recommendations contained in the Cass Review raise. It focuses, in particular, on the recommendation that hormonal treatment in the ...