The 49ers have been decimated on the defensive side of the football, including key players in linebacker Fred Warner, edge rusher Nick Bosa and rookie first-round-rookie defensive lineman Mykel ...

We put all 32 NFL teams into tiers based on their likelihood of making the postseason, from the Super Bowl favorites to the ...

The Bills travel to Miami to take on the Dolphins at Hard Rock Stadium Sunday. Follow for updates all game long.

In the world of professional football, the ability to adapt is paramount, especially when managing a young defense. Robert Saleh, the defensive coordinator for the San Francisco 49ers, is currently ...

A mind-boggling stat highlights the San Francisco 49ers’ brutal injury luck under coach Kyle Shanahan since 2017.

The 49ers got a win against the New York Giants in Week 9, but they may have lost Mykel Williams for the season.

A big domino falls for the Patriots ahead of the trade deadline with the team reportedly trading defensive end Keion White to ...

Not long after nearly losing a fumble on a sack, Mac Jones finally unravels for the 49ers, tossing a deep pick to Jamel Dean ...

The Bills and Chiefs faced off in an epic AFC showdown in Week 9. USA Today Sports provided the latest updates and more from ...

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

Down 16-0, the 49ers came alive with last-minute theatrics before halftime, highlighted by Kittle’s 17-yard, third-down touchdown catch. Setting up that score was Brian Robinson’s 46-yard kick return ...

Sunday Night Football heads to the West Coast in Week 7 when the Atlanta Falcons (3-2) visit the injury-riddled San Francisco 49ers (4-2). This is SNF’s first trip to Levi’s Stadium this season, which ...