The GTA 4 story is "really dark" because Rockstar's co-founder was "single and miserable" while making it: "We constantly thought we may be shut down"

GTA 4 is a noticeably darker and more dour game than anything the series had put out before or since, but a lot of that ...
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As Much As I Want Red Dead Redemption 3 to Happen, GTA 6 Could Change My Mind

I hope Red Dead Redemption 3 happens, but with GTA 6 confirmed to be missing a key Rockstar component, the game may change my mind.