RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

Nano-tRNAseq is based on nanopore sequencing, a technology that can directly sequence individual RNA molecules by passing them through a small pore. Each of the nucleotides that compose an RNA ...

There are 12 members of the SR protein family. This family of RNA-binding proteins is most known for RNA splicing. SRSF1 oversees the splicing of over 1,500 different messenger RNA transcripts.

Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs).

Aberrant mRNA translation is a prominent feature in many neurodegenerative diseases. The pathological hallmark is abnormally folded protein aggregates, with a unique molecular composition.

BSF also binds to the 5′ untranslated region of petA and activates its translation. BSF displayed nucleic-acid-melting activity in vitro, and its absence induces structural changes to target RNAs in ...

Study: Inexpensive and colorimetric RNA detection by E. coli cell-free protein synthesis platform at room temperature. Image Credit: Orpheus FX/Shutterstock *Important notice: medRxiv publishes ...

Luciana Coutinho de Oliveira, Laurent Volpon, Amanda K. Rahardjo, Michael J. Osborne, Biljana Culjkovic-Kraljacic, Christian Trahan, Marlene Oeffinger, Benjamin H. Kwok, Katherine L. B. Borden, ...