An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

The three-dimensional structure of a protein involved in the assembly of actin filaments could help to settle a long-standing scientific debate about the regulation of cytoskeletal organization. The ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

The formation of the branched actin networks is essential for cell polarity, but it remains unclear how the debranching activity of actin filaments contributes to this process. Here, we showed that an ...

Actin filaments are part of the cell skeleton and essential for stability and motility. They form a network that dynamically builds up and gets broken down by the addition or detachment of building ...

Biophysicists have gained a new insight about the dynamics of cellular movement, which is key to processes ranging from stem-cell differentiation and wound healing to the development of diseases such ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...

Members of the cofilin/ADF family of proteins sever actin filaments, increasing the number of filament ends available for polymerization or depolymerization. Cofilin binds actin filaments with ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...