The 2025 NFL season is in full swing, and Week 2 is on the horizon. As is the case every week, injuries are slated to play a major role over the course of the second week of the regular season, which includes the San Francisco 49ers, who continue to get bludgeoned, this time revolving around quarterback Brock Purdy .

Last week, the team allowed 32 points in a narrow win. This week, the Seattle Seahawks dropped 31 points on Pittsburgh in a 14-point road victory. Sam Darnold had two touchdowns and two interceptions, while Kenneth Walker III added 105 rushing yards as Seattle picked up its first win of the season.

We're six weeks into the NFL season, and there are surprises around the league. It's still early, but some of the teams we initially thought would be

Sam Farmer makes his picks and predictions for NFL Week 3, with the Rams upsetting the Eagles on the road and the Chargers going 3-0 against the AFC West.

The Chiefs have already lost to the Chargers, Eagles and Jaguars, and now, they get their toughest test of the season in the Detroit Lions. The Lions will be rolling into Kansas City on a four-game winning streak, which is currently the longest in the NFL.