To gain insight into why antibody responses to malarial antigens tend to be short lived, we studied antigen-specific memory B cells from donors in an area where malaria is endemic. We compared ...

New ‘copy-paste’ mechanism in genetics have been identified by researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) in a malaria parasite Plasmodium falciparum as per a study published ...

Plasmodium falciparum is responsible for the most virulent form of human malaria. This protozoan parasite spends part of its lifecycle inside the red blood cells (RBCs) of its host. The mature human ...

Background. Molecular mechanisms involved in the pathogenesis of severe Plasmodium falciparum malaria—specifically, cerebral malaria—are still unclear. Transforming growth factor β (TGF-β) family ...

Several observations point toward the possibility of a vaccine development strategy against the disease-associated blood stage form of the malaria parasite. Protection against clinical malaria ...

Scientists have identified the regional character to Plasmodium falciparum across Africa. Malaria, infecting 219 million individuals in 2017, remains a threat to public health and regional stability.

According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection.

The idea of completely eradicating malaria is becoming increasingly elusive, nevertheless the control of Plasmodium falciparum populations is a promising research avenue for limiting its spread. With ...

Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials. Two studies show that Plasmodium—the genus ...

The development and implementation of a malaria vaccine would constitute a major breakthrough for global health. Recently, numerous new candidates have entered clinical testing, following strategies ...