The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
Scientists manufacture many biotherapeutic products in immortalized cell lines, most commonly HEK293. Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences ...
A study led by scientists at NYU Langone Health and its Perlmutter Cancer Center has shown that monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer ...
Scientists have found evidence of multiple infectious diseases that may have played key roles in the army’s catastrophic ...
He was the first to use PCR testing on crime-scene DNA, inspiring a practice that has freed thousands of wrongfully convicted people. By Michael S. Rosenwald The forensic scientist Edward T. Blake ...