The NFC West is loaded at the top, and two of the division's contenders meet on Sunday when the 6-3 San Francisco 49ers host the 6-2 Los Angeles Rams. This is the second meeting between these two rivals, as the 49ers won the Week 5 matchup 26-23 in overtime on Thursday Night Football.

The NFL season continues in Week 10 when the San Francisco 49ers host the Los Angeles Rams on Sunday. Start time, how to watch, streaming and NFL TV schedule.

The Patriots hold firm at No. 2 while the Seahawks, Rams, Colts and Broncos all climb, poised to pounce should the defending champs falter.

Nate Tice & Charles McDonald give their instant reactions and takeaways from Week 10 of NFL action, starting off with the Late Hit, where they give their thoughts on the Los Angeles Chargers shutting down the Pittsburgh Steelers on Sunday night.

Matthew Stafford is one of the top-performing players in the NFL, throwing for 20 touchdowns and zero interceptions in his last six games.

Tom Brady likes what he's seeing from the Rams, but there's one glaring area of improvement he believes is holding them back.

Seattle has been on a roll lately, with a suffocating defense and virtuoso performances by Sam Darnold and Jaxon Smith-Njigba. On the Rams side, Matthew Stafford is playing at an MVP level once again. He torched the 49ers for four TDs, giving him 13 TDs in the last 3 games. Stafford has a 25/2 TD/INT ratio at the ripe, young age of 37.

NFL Research spotlights the best nuggets from each slate of games. Here are the most eye-popping statistical accomplishments from Week 10 of the 2025 season.

The Los Angeles Rams earned a statement 42-26 win over the San Francisco 49ers on Sunday, improving to 7-2 behind another stellar performance from veteran quarterback Matthew Stafford, who’s playing some of the best football of his career in his 17th NFL season.

Harrison Mevis played his first NFL game on Sunday against the 49ers and put together a clean stat sheet in his debut.